期刊名：Livers

期刊主页：https://www.mdpi.com/journal/livers

全球消除病毒性肝炎已成为国际共同目标。本期编辑荐读精选Livers 16 篇相关文献，汇总该领域最新研究进展。希望这些优质成果能为肝病领域专家、学者与临床从业者提供参考与启发，助力推进全球病毒性肝炎消除工作。

1. The Hepatitis B Virus PreS1/HBsAg Ratio Is a Predictive Marker for the Occurrence of Hepatocellular Carcinoma

乙型肝炎病毒 PreS1/HBsAg 比值是肝细胞癌发生的预测标志物

http://www.mdpi.com/2673-4389/4/3/26

Kosaka, M.; Fujino, H.; Tsuge, M.; Uchikawa, S.; Ono, A.; Murakami, E.; Kawaoka, T.; Miki, D.; Hayes, C.N.; Oka, S. The Hepatitis B Virus PreS1/HBsAg Ratio Is a Predictive Marker for the Occurrence of Hepatocellular Carcinoma. Livers 2024, 4, 364-376. https://doi.org/10.3390/livers4030026

2. The Epidemiology of Chronic Hepatitis C: Where We Are Now

慢性丙型肝炎的流行病学：我们现在所处的位置

http://www.mdpi.com/2673-4389/4/2/13

Stasi, C.; Milli, C.; Voller, F.; Silvestri, C. The Epidemiology of Chronic Hepatitis C: Where We Are Now. Livers 2024, 4, 172-181. https://doi.org/10.3390/livers4020013

3. Completeness of Initial Laboratory Evaluation Impacts Chronic Hepatitis B Outcomes

初诊实验室检查的完善程度影响慢性乙型肝炎患者的预后

http://www.mdpi.com/2673-4389/6/1/5

Imsirovic, H.; Hung, J.-H.; Dumicho, A.Y.; Manuel, D.; MacFadden, D.R.; Cooper, C.L. Completeness of Initial Laboratory Evaluation Impacts Chronic Hepatitis B Outcomes. Livers 2026, 6, 5. https://doi.org/10.3390/livers6010005

4. Epidemiology and Clinical Outcomes in the 20-Year HepCoVe Cohort: Progress Toward Elimination of HCV Infection in North-East Italy

HepCoVe 20 年队列研究的流行病学和临床结果：意大利东北部消除丙型肝炎病毒感染的进展

http://www.mdpi.com/2673-4389/6/1/7

Cavalletto, L.; Bernardinello, E.; Mezzocolli, I.; De Carlo, S.; Schipilliti, M.; Bertoli, E.; Chemello, L. Epidemiology and Clinical Outcomes in the 20-Year HepCoVe Cohort: Progress Toward Elimination of HCV Infection in North-East Italy. Livers 2026, 6, 7. https://doi.org/10.3390/livers6010007

5. Intrinsic Immune Response of HBV/HDV-Infected Cells and Corresponding Innate (Like) Immune Cell Activation

HBV/HDV感染细胞的固有免疫反应及相应的先天（样）免疫细胞活化

http://www.mdpi.com/2673-4389/4/4/40

Groth, C.; Wupper, S.; Gnouamozi, G.E.; Böttcher, K.; Cerwenka, A. Intrinsic Immune Response of HBV/HDV-Infected Cells and Corresponding Innate (Like) Immune Cell Activation. Livers 2024, 4, 562-593. https://doi.org/10.3390/livers4040040

6. Serological Status of Vaccine and Hepatitis B Virus Exposure Among Children Under 5 and Aged 15–17 Years in Kampala, Uganda

乌干达坎帕拉5岁以下和15-17岁儿童疫苗接种和乙型肝炎病毒暴露的血清学状况

http://www.mdpi.com/2673-4389/4/4/39

Muwanda, F.; Kiyonga, E.; Nambafu, J.; Turyamubona, A.; Kafeero, H.M.; Kigozi, E.; Babikako, H.M.; Wekiya, E.; Mboowa, G.; Kateete, D.P.; et al. Serological Status of Vaccine and Hepatitis B Virus Exposure Among Children Under 5 and Aged 15–17 Years in Kampala, Uganda. Livers 2024, 4, 550-561. https://doi.org/10.3390/livers4040039

7. Useful Predictor for Exacerbation of Esophagogastric Varices after Hepatitis C Virus Eradication by Direct-Acting Antivirals

丙型肝炎病毒经直接抗病毒药物根除后，食管胃底静脉曲张加重的有效预测指标

http://www.mdpi.com/2673-4389/4/3/25

Nagaoki, Y.; Yamaoka, K.; Fujii, Y.; Uchikawa, S.; Fujino, H.; Ono, A.; Murakami, E.; Kawaoka, T.; Miki, D.; Aikata, H.; et al. Useful Predictor for Exacerbation of Esophagogastric Varices after Hepatitis C Virus Eradication by Direct-Acting Antivirals. Livers 2024, 4, 352-363. https://doi.org/10.3390/livers4030025

8. Predominance of Genotype 5 Hepatitis Delta Virus Infection in a Portuguese Hepatology Unit

葡萄牙肝病科中5型丁型肝炎病毒感染占主导地位

http://www.mdpi.com/2673-4389/4/3/28

Cardoso, M.F.; Coelho, H.; Branco, J.C.e.; Bragança, S.; Alexandrino, G.; Costa, M.N.; Carvalho, R.; Pádua, E.; Martins, A. Predominance of Genotype 5 Hepatitis Delta Virus Infection in a Portuguese Hepatology Unit. Livers 2024, 4, 388-397. https://doi.org/10.3390/livers4030028

9. Hepatitis C Infection Confirmation and Fewer Visits Contribute to Improving Treatment Rates in a Predominantly African American Health Center

丙型肝炎感染确诊与就诊频次优化，可提升非裔美国人为主医疗机构的治疗率

http://www.mdpi.com/2673-4389/4/4/41

Auguste, C.; Khamis, R.; Naylor, P.; Mutchnick, M. Hepatitis C Infection Confirmation and Fewer Visits Contribute to Improving Treatment Rates in a Predominantly African American Health Center. Livers 2024, 4, 594-600. https://doi.org/10.3390/livers4040041

10. Effects of SARS-CoV-2 Spike S1 Subunit on the Interplay Between Hepatitis B and Hepatocellular Carcinoma Related Molecular Processes in Human Liver

SARS-CoV-2 刺突蛋白 S1 亚基对人肝脏中乙型肝炎和肝细胞癌相关分子过程相互作用的影响

http://www.mdpi.com/2673-4389/5/1/1

Colonna, G. Effects of SARS-CoV-2 Spike S1 Subunit on the Interplay Between Hepatitis B and Hepatocellular Carcinoma Related Molecular Processes in Human Liver. Livers 2025, 5, 1. https://doi.org/10.3390/livers5010001

11. Hepatocellular Carcinoma in Delta Hepatitis Versus HBV Monoinfection: Spot the Differences

丁型肝炎合并感染与单一乙型肝炎感染背景下的肝细胞癌：解析二者区别

http://www.mdpi.com/2673-4389/5/2/23

Cerban, R.; Chitul, M.; Iacob, S.; Gheorghe, D.; Stan, D.G.; Gheorghe, L. Hepatocellular Carcinoma in Delta Hepatitis Versus HBV Monoinfection: Spot the Differences. Livers 2025, 5, 23. https://doi.org/10.3390/livers5020023

12. Hepatitis C Virus Opportunistic Screening in South-Eastern Tuscany Residents Admitted to the University Hospital in Siena

在锡耶纳大学医院接受治疗的托斯卡纳东南部居民中开展丙型肝炎病毒机会性筛查

http://www.mdpi.com/2673-4389/5/3/30

Stasi, C.; Marzotti, T.; Nassi, F.; Giugliano, G.; Pacini, S.; Rentini, S.; Accioli, R.; Macchiarelli, R.; Gennari, L.; Lazzerini, P.E.; et al. Hepatitis C Virus Opportunistic Screening in South-Eastern Tuscany Residents Admitted to the University Hospital in Siena. Livers 2025, 5, 30. https://doi.org/10.3390/livers5030030

13. Indeterminate-Grey Zone of HBeAg-Negative Chronic Hepatitis B Is Associated with a Higher Risk of Hepatocellular Carcinoma Compared to HBeAg-Negative Chronic Infection—A Systematic Review and Meta-Analysis

HBeAg阴性慢性乙型肝炎的灰色地带与更高的肝细胞癌风险相关——系统评价和荟萃分析

http://www.mdpi.com/2673-4389/6/1/9

Syrigou, R.; Tiganiti, D.; Kintzoglanakis, K.; Lekakis, V.; Karagiannakis, D.S. Indeterminate-Grey Zone of HBeAg-Negative Chronic Hepatitis B Is Associated with a Higher Risk of Hepatocellular Carcinoma Compared to HBeAg-Negative Chronic Infection—A Systematic Review and Meta-Analysis. Livers 2026, 6, 9. https://doi.org/10.3390/livers6010009

14. Intestinal Microbiota and Hepatitis C: Dysbiosis During the Natural History of the Disease and Treatment

肠道菌群与丙型肝炎：疾病自然史及治疗过程中的菌群失调

http://www.mdpi.com/2673-4389/6/1/11

Fumero León, F.J.; Pujol, F.H. Intestinal Microbiota and Hepatitis C: Dysbiosis During the Natural History of the Disease and Treatment. Livers 2026, 6, 11. https://doi.org/10.3390/livers6010011

15. Identification of Unrecognized Hepatitis B, C, and D Infections Through the Private Laboratory-Based RE-LINK Screening Project in Romania: A Micro-Elimination Initiative

通过罗马尼亚私营实验室开展的 RE-LINK 筛查项目识别未被发现的乙型、丙型和丁型肝炎感染：一项微消除计划

http://www.mdpi.com/2673-4389/6/1/13

Gheorghe, L.; Curici, A.; Iacob, S. Identification of Unrecognized Hepatitis B, C, and D Infections Through the Private Laboratory-Based RE-LINK Screening Project in Romania: A Micro-Elimination Initiative. Livers 2026, 6, 13. https://doi.org/10.3390/livers6010013

16. Comparison of Differentially Expressed Genes in Human Versus in Chimeric Mouse Livers Following HBV Infection

乙肝病毒感染后人肝与嵌合小鼠肝中差异表达基因的比较

http://www.mdpi.com/2673-4389/5/2/18

Bao, H.; Tsuge, M.; Murakami, S.; Fujii, Y.; Uchikawa, S.; Fujino, H.; Ono, A.; Murakami, E.; Kawaoka, T.; Miki, D.; et al. Comparison of Differentially Expressed Genes in Human Versus in Chimeric Mouse Livers Following HBV Infection. Livers 2025, 5, 18. https://doi.org/10.3390/livers5020018

关于 Livers

Livers期刊主题涵盖肝炎 所有形式；酒精性肝病；非酒精性脂肪性肝病和非酒精性脂性肝炎；肝硬化；胆道疾病；药物性肝损伤；遗传性和代谢性肝病及其并发症；癌症与药物代谢；肝细胞癌；肝纤维化；肝病免疫学；肝病学营养；肝病病理学；肝病的诊断和治疗，为肝病学多学科领域的基础、转化和高级临床研究提供平台。目前已被 ESCI（Web of Science）、Scopus 等国际权威数据库收录。

	主编： Prof. Dr. Hartmut W. Jaeschke University of Kansas Medical Center, USA
	副主编：Prof. Dr. Ralf Weiskirchen RWTH University Hospital Aachen, Germany