期刊名：Toxics

期刊主页：https://www.mdpi.com/journal/toxics

本期精选了2024-2025年发表于Toxics期刊“人类毒理学与流行病”栏目的15篇代表性论文。文章主题涵盖内分泌干扰物暴露评估、纳米毒理学、生殖毒性、新兴污染物毒性等多个重要研究方向，集中展现了该领域的最新进展与研究方法。希望能展现目前该领域内的研究进展与趋势，为相关领域学者提供信息与参考。

1. Cement Industry Pollution and Its Impact on the Environment and Population Health: A Review

水泥工业污染及其对环境与公众健康的影响：综述

https://www.mdpi.com/2305-6304/13/7/587

B?rbulescu, A.; Hosen, K. Cement Industry Pollution and Its Impact on the Environment and Population Health: A Review. Toxics 2025, 13(7), 587. https://doi.org/10.3390/toxics13070587

2. Polyhexamethylene Guanidine Phosphate Enhanced Procoagulant Activity through Oxidative-Stress-Mediated Phosphatidylserine Exposure in Platelets

聚六亚甲基胍磷酸盐通过氧化应激诱导血小板磷脂酰丝氨酸外翻，从而增强其促凝血活性

https://www.mdpi.com/2305-6304/12/1/50

Choi, J. H.; Kim, K. Polyhexamethylene Guanidine Phosphate Enhanced Procoagulant Activity through Oxidative-Stress-Mediated Phosphatidylserine Exposure in Platelets. Toxics 2024, 12(1), 50. https://doi.org/10.3390/toxics12010050

3. Prenatal Perfluoroalkyl Substance Exposure in Association with Global Histone Post-Translational Methylation in 2-Year-Old Children

产前全氟烷基物质暴露与2岁儿童组蛋白全局翻译后甲基化的关联研究

https://www.mdpi.com/2305-6304/12/12/876

Tsai, W.-J.; Hsieh, W.-S.; Chen, P.-C.; Liu, C.-Y. Prenatal Perfluoroalkyl Substance Exposure in Association with Global Histone Post-Translational Methylation in 2-Year-Old Children. Toxics 2024, 12(12), 876. https://doi.org/10.3390/toxics12120876

4. Fertilizers and Human Health—A Systematic Review of the Epidemiological Evidence

肥料与人类健康——流行病学证据的系统性综述

https://www.mdpi.com/2305-6304/12/10/694

Tagkas, C. F.; Rizos, E. C.; Markozannes, G.; Karalexi, M. A.; Wairegi, L.; Ntzani, E. E. Fertilizers and Human Health—A Systematic Review of the Epidemiological Evidence. Toxics 2024, 12(10), 694. https://doi.org/10.3390/toxics12100694

5. Toxicological Effects of Naturally Occurring Endocrine Disruptors on Various Human Health Targets: A Rapid Review

天然存在的内分泌干扰物对人类多种健康目标的毒性影响：快速综述

https://www.mdpi.com/2305-6304/12/4/256

Virtuoso, S.; Raggi, C.; Maugliani, A.; Baldi, F.; Gentili, D.; Narciso, L. Toxicological Effects of Naturally Occurring Endocrine Disruptors on Various Human Health Targets: A Rapid Review. Toxics 2024, 12(4), 256. https://doi.org/10.3390/toxics12040256

6. Unveiling the Mysteries of Contrast-Induced Acute Kidney Injury: New Horizons in Pathogenesis and Prevention

揭开对比诱发急性肾损伤的奥秘：发病机制与预防的新视野

https://www.mdpi.com/2305-6304/12/8/620

Wang, Z.; Wang, Q.; Gong, X. Unveiling the Mysteries of Contrast-Induced Acute Kidney Injury: New Horizons in Pathogenesis and Prevention. Toxics 2024, 12(8), 620. https://doi.org/10.3390/toxics12080620

7. Phthalates and Non-Phthalate Plasticizers and Thyroid Dysfunction: Current Evidence and Novel Strategies to Reduce Their Spread in Food Industry and Environment

邻苯二甲酸盐与非邻苯二甲酸盐增塑剂与甲状腺功能障碍：现有证据及减少其在食品工业及环境中的扩散的新策略

https://www.mdpi.com/2305-6304/13/3/222

Gorini, F.; Tonacci, A.; Sanmartin, C.; Venturi, F. Phthalates and Non-Phthalate Plasticizers and Thyroid Dysfunction: Current Evidence and Novel Strategies to Reduce Their Spread in Food Industry and Environment. Toxics 2025, 13(3), 222. https://doi.org/10.3390/toxics13030222

8. Bisphenol A Exposure Interferes with Reproductive Hormones and Decreases Sperm Counts: A Systematic Review and Meta-Analysis of Epidemiological Studies

双酚A暴露干扰生殖激素并降低精子数量：流行病学研究的系统综述与荟萃分析

https://www.mdpi.com/2305-6304/12/4/294

Lü, L.; Liu, Y.; Yang, Y.; He, J.; Luo, L.; Chen, S.; Xing, H. Bisphenol A Exposure Interferes with Reproductive Hormones and Decreases Sperm Counts: A Systematic Review and Meta-Analysis of Epidemiological Studies. Toxics 2024, 12(4), 294. https://doi.org/10.3390/toxics12040294

9. Differential Disruption of Glucose and Lipid Metabolism Induced by Phthalates in Human Hepatocytes and White Adipocytes

邻苯二甲酸酯在人体肝细胞和白色脂肪细胞中对糖脂代谢的差异性干扰

https://www.mdpi.com/2305-6304/12/3/214

Tian, Y.; Xu, M.; Shang, H.; You, L.; Yang, J.; Jia, X.; Yang, H.; Wu, Y.; Yang, X.; Wan, Y. Differential Disruption of Glucose and Lipid Metabolism Induced by Phthalates in Human Hepatocytes and White Adipocytes. Toxics 2024, 12(3), 214. https://doi.org/10.3390/toxics12030214

10. The Impact of Ambient Air Pollution on Allergic Rhinitis Symptoms: A Prospective Follow-Up Study

环境空气污染对过敏性鼻炎症状的影响：一项前瞻性随访研究

https://www.mdpi.com/2305-6304/12/9/663

Sun, W.; Ding, C.; Jiang, Z.; Zheng, X.; Jiang, J.; Xu, H. The Impact of Ambient Air Pollution on Allergic Rhinitis Symptoms: A Prospective Follow-Up Study. Toxics 2024, 12(9), 663. https://doi.org/10.3390/toxics12090663.

11. Micro- and Nanoplastics and Fetal Health: Challenges in Assessment and Evidence from Epidemiological Studies

微塑料和纳米塑料与胎儿健康：评估中的挑战及流行病学研究证据

https://www.mdpi.com/2305-6304/13/5/388

Sekovanic, A.; Orct, T.; Kljakovic-Gašpic, Z. Micro- and Nanoplastics and Fetal Health: Challenges in Assessment and Evidence from Epidemiological Studies. Toxics 2025, 13(5), 388. https://doi.org/10.3390/toxics13050388

12. A Rapid In Vivo Toxicity Assessment Method for Antimicrobial Peptides

一种用于抗菌肽的体内快速毒性评估方法

https://www.mdpi.com/2305-6304/12/6/387

Chi, Y.; Peng, Y.; Zhang, S.; Tang, S.; Zhang, W.; Dai, C.; Ji, S. A Rapid In Vivo Toxicity Assessment Method for Antimicrobial Peptides. Toxics 2024, 12(6), 387. https://doi.org/10.3390/toxics12060387.

13. Which Environmental Pollutants Are Toxic to Our Ears?—Evidence of the Ototoxicity of Common Substances

哪些环境污染物会对我们的耳朵造成毒性影响？——常见物质的耳毒性证据

https://www.mdpi.com/2305-6304/12/9/650

Zarus, G. M.; Ruiz, P.; Benedict, R.; Brenner, S.; Carlson, K.; Jeong, L.; Morata, T. C. Which Environmental Pollutants Are Toxic to Our Ears?—Evidence of the Ototoxicity of Common Substances. Toxics 2024, 12(9), 650. https://doi.org/10.3390/toxics12090650

14. The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice

灵芝活性肽 GLP4 对镉中毒所致小鼠肺损伤的保护作用

https://www.mdpi.com/2305-6304/12/6/378

Zhu, S.; Wang, X.; Liu, G. The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice. Toxics 2024, 12(6), 378. https://doi.org/10.3390/toxics12060378.

15. The Effect of Selenium Against Cadmium-Induced Nephrotoxicity in Rats: The Role of the TRPM2 Channel

硒对镉所致大鼠肾毒性的影响：TRPM2 通道的作用

https://www.mdpi.com/2305-6304/13/2/87

Kele?, Ö. F.; Bayir, M. H.; Çiçek, H. A.; Ahlatc?, A.; Y?ld?zhan, K. The Effect of Selenium Against Cadmium-Induced Nephrotoxicity in Rats: The Role of the TRPM2 Channel. Toxics 2025, 13(2), 87. https://doi.org/10.3390/toxics13020087.

栏目介绍：Human Toxicology and Epidemiology 人类毒理学与流行病

栏目链接：https://www.mdpi.com/journal/toxics/sections/environmental_epidemiology

“人类毒理学与流行病”栏目聚焦于展示环境中的有毒物质对人类健康影响的研究成果。栏目诚邀提交高质量的原创研究、综述，以及有毒物质暴露与人类健康结果之间的关联（包括但不限于神经、生殖、内分泌、心血管或免疫方面）的评论和分析。这些暴露可能涉及环境或职业方面的研究，例如对工业化学品、杀虫剂、金属、吸烟和酒精的暴露。欢迎关于所有生命阶段（包括孕期）暴露后健康影响的研究。

栏目主编：Gunnar Toft博士，丹麦奥胡斯大学公共卫生学院。研究方向为流行病学，生物标志物以及生殖毒理学。

Toxics 期刊介绍

期刊名：Toxics (ISSN 2305-6304)

主编：Demetrio Raldúa, IDAEA-CSIC, Spain

期刊发表与有毒有害化学物质和材料相关的学术文章，主题范围涵盖毒理学、生态毒理学、环境科学、环境工程、环境化学和流行病学等学科。期刊已被Web of Science、PubMed和Scopus等多个数据库收录。目前期刊位于JCR毒理学一区和环境科学二区。