期刊名：Antioxidants

期刊主页：https://www.mdpi.com/journal/antioxidants

阿尔茨海默病（AD）是全球范围内严重威胁老年人生命健康的神经退行性疾病，其发病隐匿、进行性发展，给患者、家庭及社会带来沉重负担。近年来，针对AD关键病理环节的干预策略研究持续深入。本期文献清单精选多篇前沿论著，涵盖病理机制探究、天然活性产物及肠道微生态调控等多个维度，围绕β-淀粉样蛋白（Aβ）毒性、tau蛋白病变、线粒体功能障碍、代谢紊乱及神经炎症等核心病理机制展开深度探究，阐释氧化应激、神经炎症及线粒体质量控制等关键生物学过程调控AD进展的分子通路，同时挖掘各类天然活性物质与微生态干预手段的神经保护效应及作用机制，系统呈现了AD发生发展中的核心机制、关键调控通路与潜在治疗策略，旨在为揭示阿尔茨海默病的发病机制、推动临床转化研究及开发新型干预手段提供有力的学术支撑与参考视角。

1. The Dual Role of Amyloid Beta-Peptide in Oxidative Stress and Inflammation: Unveiling Their Connections

β-淀粉样肽在氧化应激与炎症中的双重作用：揭示其在阿尔茨海默病病因病理中的关联

https://www.mdpi.com/2076-3921/13/10/1208

Fanlo-Ucar, H.; Picón-Pagès, P.; Herrera-Fernández, V.; ILL-Raga, G.; Muñoz, F.J. The Dual Role of Amyloid Beta-Peptide in Oxidative Stress and Inflammation: Unveiling Their Connections in Alzheimer’s Disease Etiopathology. Antioxidants 2024, 13, 1208.

2. Oxidative Stress, Advanced Glycation End Products (AGEs), and Neurodegeneration in Alzheimer‘s Disease: A Metabolic Perspective

氧化应激、晚期糖基化终末产物（AGEs）与阿尔茨海默病中的神经退行性变：基于代谢视角的探讨

https://www.mdpi.com/2076-3921/14/9/1044

Boccardi, V.; Mancinetti, F.; Mecocci, P. Oxidative Stress, Advanced Glycation End Products (AGEs), and Neurodegeneration in Alzheimer’s Disease: A Metabolic Perspective. Antioxidants 2024, 15, 1044.

3. CoQ10 and Mitochondrial Dysfunction in Alzheimer‘s Disease

辅酶Q10与阿尔茨海默病中的线粒体功能障碍

https://www.mdpi.com/2076-3921/13/2/191

Fišar, Z.; Hroudová, J. CoQ10 and Mitochondrial Dysfunction in Alzheimer’s Disease. Antioxidants 2024, 13, 191.

4. Mitochondrial Quality Control in Alzheimer’s Disease: Insights from Caenorhabditis elegans Models

阿尔茨海默病中的线粒体质量控制：来自秀丽隐杆线虫模型的启示

https://www.mdpi.com/2076-3921/13/11/1343

Ganguly, U.; Carroll, T.; Nehrke, K.; Johnson, G.V.W. Mitochondrial Quality Control in Alzheimer’s Disease: Insights from Caenorhabditis elegans Models. Antioxidants 2024, 13, 1343.

5. Lactobacillus Eats Amyloid Plaque and Post-Biotically Attenuates Senescence Due to Repeat Expansion Disorder and Alzheimer‘s Disease

乳杆菌“吞噬”淀粉样斑块并通过后生元效应延缓重复扩增障碍与阿尔茨海默病相关的衰老

https://www.mdpi.com/2076-3921/13/10/1225

Tyagi, S.C. Lactobacillus Eats Amyloid Plaque and Post-Biotically Attenuates Senescence Due to Repeat Expansion Disorder and Alzheimer’s Disease. Antioxidants 2024, 13, 1225.

6. Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-like Behavior in the 5xFAD Mouse Model of Alzheimer’s Disease

南非醉茄（Ashwagandha）可改善5xFAD阿尔茨海默病小鼠模型的空间记忆、焦虑及抑郁样行为

https://www.mdpi.com/2076-3921/13/10/1164

Gladen-Kolarsky, N.; Monestime, O.; Bollen, M.; Choi, J.; Yang, L.; Magaña, A.A.; Maier, C.S.; Soumyanath, A.; Gray, N.E. Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-like Behavior in the 5xFAD Mouse Model of Alzheimer’s Disease. Antioxidants 2024, 13, 1164.

7. CRISPR/Cas9 and iPSC-Based Therapeutic Approaches in Alzheimer’s Disease

基于CRISPR/Cas9和iPSC的阿尔茨海默病治疗策略

https://www.mdpi.com/2076-3921/14/7/781

Raffaele, I.; Cipriano, G.L.; Anchesi, I.; Oddo, S.; Silvestro, S. CRISPR/Cas9 and iPSC-Based Therapeutic Approaches in Alzheimer’s Disease. Antioxidants 2025, 14, 781.

期刊介绍

主编：Prof. Dr. Alessandra Napolitano, University of Naples “Federico II”,Italy;

副主编：刘健康教授，西安交通大学/康复大学，中国

Antioxidants (ISSN 2076-3921) 是一个国际型开放获取英文学术期刊，期刊为抗氧化剂科学和技术的相关研究提供了一个发表平台，重点关注活性物种、生物相关过程、天然产物和食品中活性物质的抗氧化性能、作用机制、应用和用途的新见解和想法。期刊在 Web of Science Journal Citation Reports 数据库的 Medicinal Chemistry、Food Science & Technology 和 Biochemistry & Molecular Biology 三个分区中皆为 1 区。期刊5年 IF 为8.5。

2025 Impact Factor：8.2

2025 CiteScore：14.7

Time to First Decision：18.7 Days

Acceptance to Publication：2.9 Days